About DMPS

What is DMPS?
DMPS is short for Dimercaptopropanesulfonic acid (pronounced dye-mer-cap-toe-pro-pain-sull-fon-ic acid).  DMPS is called a chelating agent, which is a substance that binds to metal.  DMPS specifically binds to mercury, lead and arsenic, and forms stable complexes with these metals, allowing them to be eliminated from the body.  DMPS is water soluble, and is over 50% rapidly absorbed through oral administration.  The highest concentrations of DMPS are detected in plasma and kidneys.  Elimination of DMPS takes place to about 90% via the kidneys.

Is DMPS a Natural Substance?
DMPS is created through a series of complex chemical reactions.  It is not found in nature.  It was first developed in the 1950s in Russia for the treatment of mercury and lead poisoning and has been sold under the brand names Dimaval and Unithiol in Germany and Russia, respectively.

Is DMPS Safe?
DMPS is a substance with very low toxicity systemically and is generally well tolerated, even with long-term use.  Studies have been conducted on the lowest SINGLE oral dose of DMPS required to cause negative changes to blood chemistry in animals.  According to the studies, a 30-pound dog could consume 120 grams of DMPS at one time before blood chemistry changes were noted.  A rat could consume twice that amount.  Using the dog toxicity model, a 150-pound person would need to take 600 grams of pure DMPS at one time to note changes in blood chemistry.  By way of comparison, the amount of DMPS contained in the entire 30-day MercOut Program is just 4 grams.  Using the dog toxicity studies as a guide, a typical adult could consume 150 complete MercOut Programs at one time without serious consequences.  This is, of course, not recommended and should not be done.  Extensive animal testing in the 1950s with DMPS showed no toxicity to the immune system, heart, liver, blood orkidneys.  No significant effects on fetal development were noted when fed to pregnant mice.  We can find not reports of any human deaths from oral DMPS usage.  Even with this safety history, we do NOT provide the MercOut Program to anyone who is pregnant or lactating, or believes there is any possibility she may be pregnant.

Does DMPS Have Any Side Effects?
DMPS can weakly bond to essential minerals in the body such as copper and zinc.  In addition to the possible increased elimination of essential trace elements (especially zinc), allergic reactions in the form of skin reaction are seen in between 5-10% of individuals taking DMPS.  These reactions are much milder than with the intravenous route of administration.  Most of the reported adverse reactions to DMPS occurred on long-term therapy.  Symptoms were generally mild and included itching, nausea, dizziness, fever, weakness, skin reactions (e.g., rash, urticaria), mucous membrane reactions, raised body temperature, or shivering and fever.  Allergic reactions generally subside within 3 to 5 days of stopping DMPS treatment.  Some people may notice an odor of rotten eggs coming from body excretions (urine, sweat) while they are taking DMPS.  This is due to the sulfur nature of the DMPS chemical.

How Long Can a Person Take DMPS?
The longest period of continuous treatment of a human with DMPS reported in scientific literature was 4 1/2 years.  The longest treatment period experienced with the MercOut Program has been 5 months, with the average lasting 2 months.  Each MercOut program is 30 days, and is followed by a special urine test to determine the amount of mercury still remaining in the body.  If the test result indicates that the mercury level is still in the "Elevated" range, the physician likely would recommend another 30-day program.  The duration of treatment varies with each individual, and depends on the length and type of mercury exposure, and may also be influenced by age and gender.

Can I purchase DMPS Through My Local Vitamin or Health Food Store?
At present, only physicians and other health care practitioners can order and administer compounds containing DMPS.

Is DMPS a Prescription?  Is It Approved By The FDA?
DMPS has been in use by physicians in hospitals and private practice worldwide since the 1950s for the treatment of mercury poisoning.  At this time, DMPS has no official status with the U.S. Food and Drug Administration, and is not listed as a prescription medication.  The FDA 's web site includes this description:  "Dimercapto-1-propanesulfonic acid (DMPS), a chelating agent, is well characterized chemically.  DMPS has been used to treat heavy metal poisoning.  At doses reported in the literature for this indication, DMPS appears to be relatively nontoxic, and serious adverse reactions associated with its use have not been commonly reported.  Limited anecdotal evidence of DMPS's effectiveness for this indication is also reported in the literature." [Federal Register: Volume 64, Number 4].

How Do You Know the DMPS is 100% Pure and Free of Impurities?
MercOut International takes great care to assay each batch of DMPS it receive through the independent and highly respected Cawthron Institute in Nelson, New Zealand.  An extensive analysis ensures the purity of the DMPS to the highest pharmaceutical standards prior to encapsulation at the GMP-certified manufacturing facility.  

Can I Safely Take Other Vitamins or Medications with DMPS?
There is no known adverse interaction between any ingredient in the MercOut formula and any prescription medication, or with vitamin or herbal formulations.  HOWEVER, because DMPS may weakly bind to and remove other metals, it is not advisable to take any MINERALS either with the MercOut nighttime capsule or within two hours of taking it.  Minerals would include zinc, copper, manganese, iron, selenium, and magnesium.